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pentobarbital will lessen the extent or effect of amlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital will reduce the level or effect of vinorelbine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unknown.Contraindicated (1)pentobarbital will lessen the lev